Product Name: Genistein
Botanical Source: Genista tinctoria Linn, Sophora subprostrala Chun
et T.Chen, S.japonica L.
Specification: 98% HPLC
CAS NO.: 446-72-0
Molecular formula: C15H10O5
Molecular weight: 270.2369
Appearance: Light yellow to White powder
Place of origin: China
Description: Genistein is a phytoestrogen and belongs to the
category of isoflavones.Genistein
was first isolated in 1899 from the Dyer's broom, Genista
tinctoria; hence, the chemical name. The compound structure was
established in 1926, when it was found to be identical with
prunetol. It was chemically synthesized in 1928.
1.Anti-cancer. The main known activity of genistein is tyrosine
kinase inhibitor, mostly of epidermal growth factor receptor
(EGFR). Genistein can fight against cancer by inhibiting the
activity of protein tyrosine kinase and inhibits the
phosphorylation of intracellular proteins.
2.Antioxidant. Genistein may act as direct antixodant, similar to
many other isoflavones , and thus may alleviate damaging effects of
free radicals in tissues.
3. Effects on atherosclerotic. Genistein protects against
pro-inflammatory factor-induced vascular endothelial barrier
dysfunction and inhibits leukocyte endothelium interaction, thereby
modulating vascular inflammation, a major event in the pathogenesis
pathogenesis of atherosclerosis.
4.Genistein and other isoflavones have been identified as
angiogeesis inhibitors, and found to inhibit the uncontrolled cell
growth of cancer, most likely by inhibiting the activity of
substance in the body that regulate cell devision and cell survival
5.Genistein was found to be the major isoflavone responsible for
the deworming property. Genistein was subsequently demonstrated to
be highly effective against intestinal parasites.
6.Genistein can bind to estrogen receptors, play a weak
estrogen-like effects,increaes bone density , and prevent bone
loss, to treat osteoporosis.
1. Applied in pharmaceutical field, it can be made into
suppository, lotion, injection, tablets,
2. Applied in health product field, it is mainly used in female
health product and health medicine
for delaying aging and preventing hematological disease and cancer.
Storage: Store at cool&dry place.Protect from light,moisture
and pest infestation.
Shelf life: 2 years when properly stored.
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